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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MSH6
All Species:
11.21
Human Site:
T152
Identified Species:
17.62
UniProt:
P52701
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P52701
NP_000170.1
1360
152786
T152
K
R
L
L
K
P
Y
T
G
S
K
S
K
E
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113749
1360
152750
T152
K
R
L
L
K
P
Y
T
G
S
K
S
K
E
A
Dog
Lupus familis
XP_531814
1283
145094
V153
E
I
E
S
E
E
E
V
R
P
K
V
Q
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P54276
1358
151058
T152
K
R
M
L
K
P
Y
T
G
S
K
S
K
E
A
Rat
Rattus norvegicus
XP_002726765
1361
151628
S152
M
L
K
P
Y
T
G
S
K
S
K
E
A
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419359
1466
164165
K267
I
K
Y
L
R
P
Y
K
G
S
S
D
R
E
V
Frog
Xenopus laevis
NP_001089247
1340
149481
G152
A
A
E
T
Q
K
G
G
M
F
F
S
T
K
P
Zebra Danio
Brachydanio rerio
NP_878280
1369
153213
A152
E
Y
Q
G
S
N
S
A
V
A
K
S
G
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUM0
1190
133117
I75
A
A
K
R
K
L
P
I
S
D
D
E
P
A
S
Honey Bee
Apis mellifera
XP_392346
1120
127429
Nematode Worm
Caenorhab. elegans
NP_491163
1186
133609
S71
V
K
T
P
R
N
A
S
K
R
P
K
V
V
V
Sea Urchin
Strong. purpuratus
XP_797647
1335
149141
D152
R
R
G
M
D
Q
A
D
E
A
L
K
K
D
R
Poplar Tree
Populus trichocarpa
XP_002320307
1288
142120
E154
N
E
K
I
E
W
V
E
P
C
V
K
K
F
K
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04716
1324
146779
G152
T
F
Y
D
K
G
E
G
K
H
V
V
E
Y
E
Baker's Yeast
Sacchar. cerevisiae
Q03834
1242
140062
L127
S
T
T
T
D
E
D
L
S
S
S
Q
S
R
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.3
88.1
N.A.
85.8
86.4
N.A.
N.A.
64.2
66.5
60
N.A.
39
41.2
34.4
48.6
Protein Similarity:
100
N.A.
98.6
91.3
N.A.
92.1
92.8
N.A.
N.A.
75.4
79.9
74.9
N.A.
57.6
58
52.7
66.6
P-Site Identity:
100
N.A.
100
6.6
N.A.
93.3
13.3
N.A.
N.A.
40
6.6
13.3
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
N.A.
100
33.3
N.A.
100
26.6
N.A.
N.A.
60
20
26.6
N.A.
13.3
0
20
40
Percent
Protein Identity:
36.1
N.A.
N.A.
33.2
29
N.A.
Protein Similarity:
52
N.A.
N.A.
51.4
49.1
N.A.
P-Site Identity:
6.6
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
14
0
0
0
0
14
7
0
14
0
0
7
7
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
7
14
0
7
7
0
7
7
7
0
7
0
% D
% Glu:
14
7
14
0
14
14
14
7
7
0
0
14
7
27
7
% E
% Phe:
0
7
0
0
0
0
0
0
0
7
7
0
0
7
0
% F
% Gly:
0
0
7
7
0
7
14
14
27
0
0
0
7
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% H
% Ile:
7
7
0
7
0
0
0
7
0
0
0
0
0
0
0
% I
% Lys:
20
14
20
0
34
7
0
7
20
0
40
20
34
7
14
% K
% Leu:
0
7
14
27
0
7
0
7
0
0
7
0
0
0
0
% L
% Met:
7
0
7
7
0
0
0
0
7
0
0
0
0
0
7
% M
% Asn:
7
0
0
0
0
14
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
14
0
27
7
0
7
7
7
0
7
0
7
% P
% Gln:
0
0
7
0
7
7
0
0
0
0
0
7
7
7
0
% Q
% Arg:
7
27
0
7
14
0
0
0
7
7
0
0
7
7
14
% R
% Ser:
7
0
0
7
7
0
7
14
14
40
14
34
7
0
14
% S
% Thr:
7
7
14
14
0
7
0
20
0
0
0
0
7
0
0
% T
% Val:
7
0
0
0
0
0
7
7
7
0
14
14
7
7
14
% V
% Trp:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
7
14
0
7
0
27
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _